A ten-year review of Candida sepsis and mortality in burn patients

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Feller-I., Thomson-P-D. Surgery. 1987 Feb. 101(2). P 213-6. A retrospective analysis of [1mCandida sepsis [m was carried out in 1722 burn patients admitted to this center from 1975 to 1984. Cultures were positive for [1mCandida [m in 233 (13.5%) of these patients during their hospitalization. Candidemia was present in 70 (4.0%) of the 1722 patients. Of the 70 patients with candidemia, 38 (54%) died. However, only 11 patients (15.7%) died of [1mCandida sepsis [m or mixed [1mCandida [m and bacterial [1msepsis [m (less than 1% of the total patient population). The remaining 27 patients who had candidemia died of bacterial septicemia or organ system failure. The low incidence of [1mCandida [m and the low incidence of mortality due to [1mCandida [m was attributed to a comprehensive program of prevention, detection, and treatment. Early initiation of treatment with amphotericin B was an important aspect of the program. Author-abstract.