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Wheeless' Textbook of Orthopaedics
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A clinical technique for prevention of spasm and preservation of ³


endothelium in saphenous vein grafts. LoGerfo FW. Haudenschild CC. Quist WC. Archives of Surgery. [JC:8ia] 119(10):1212-4, 1984 Oct. Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 degrees C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure. This technique preserves endothelial integrity in human reversed saphenous vein grafts.



Original Text by Clifford R. Wheeless, III, MD.