The Hip: Preservation, Replacement and Revision

Aspirin for DVT:

   - Basic Science:
        - Why does aspirin decrease the risk of venous thromboembolism? On old and novel antithrombotic effects of acetyl salicylic acid.
        - Aspirin for prevention and treatment of venous thromboembolism
        - Antiplatelet therapy in prevention of cardio- and venous thromboembolic events.
        - Thromboembolic prophylaxis in total joint arthroplasty

   - Preoperative ASA
        - Safety of peri-operative low-dose aspirin as a part of multimodal venous thromboembolic prophylaxis for total knee and hip arthroplasty.

   - Reduction of Infection with ASA
        -
Administration of Aspirin as a Prophylaxis Agent Against Venous Thromboembolism Results in Lower Incidence of Periprosthetic Joint Infection.

   - Papers which show that ASA is effective for DVT prophylaxis:


        - Fatal pulmonary embolism following elective total hip arthroplasty: a 12-year study.
        - Thromboembolism Prophylaxis in Hip Arthroplasty: Routine and High Risk Patients.
        - Aspirin in the primary prophylaxis of venous thromboembolism in surgical patients
        - What's New in Venous Thromboembolic Prophylaxis Following Total Knee and Total Hip Arthroplasty? An Update.
        - DVT prophylaxis after TKA: routine anticoagulation vs risk screening approach - a randomized study.
        - Risk of venous thromboembolism after shoulder arthroplasty in the Medicare population
        - Deep-vein thrombosis prophylaxis in foot and ankle surgery: what is the current state of practice?
        - Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: a systematic review and meta-analysis.
        - Aspirin combined with mechanical measures to prevent venous thromboembolism after total knee arthroplasty: a randomized controlled trial.
        - Administering aspirin, rivaroxaban and low-molecular-weight heparin to prevent deep venous thrombosis after total knee arthroplasty.
        - Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial.
        - Incidence of symptomatic thromboembolic disease after patellofemoral arthroplasty
        - Asian venous thromboembolism guidelines: prevention of venous thromboembolism.
        - Risk early warning and multimodal prevention of postoperative venous thromboembolism for hip fractures
        - Aspirin for the prophylaxis of venous thromboembolic events in orthopedic surgery patients: a comparison of the AAOS and ACCP guidelines with review of the evidence.
        - Thromboembolic events are uncommon after open treatment of proximal humerus fractures using aspirin and compression devices.
        - Venous thromboembolic disease after total hip and knee arthroplasty: current perspectives in a regulated environment.
        - Venous thromboembolic prophylaxis for hip fractures.
        - Aspirin for the prevention of recurrent venous thromboembolism: the INSPIRE collaboration.
        - Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
        - Efficacy and safety of aspirin in prevention of venous thromboembolism after total joint arthroplasty
        - Aspirin prophylaxis for thromboembolic disease after total joint arthroplasty
        - Symptomatic thromboembolism after one-stage bilateral THA with a multimodal prophylaxis protocol.
        - Mechanical calf compression and aspirin prophylaxis for total knee arthroplasty
        - The incidence and prevention of symptomatic thromboembolic disease following unicompartmental knee arthroplasty.
        - The benefit of aspirin chemoprophylaxis for thromboembolism after total knee arthroplasty
        - Aspirin for preventing the recurrence of venous thromboembolism.
        - Aspirin and the prevention of venous thromboembolism.
        - Aspirin: An Alternative for Pulmonary Embolism Prophylaxis After Arthroplasty?
        - Fatal Pulmonary Embolism following Achilles Tendon Repair: A Case Report and a Review of the Literature.
        - Aspirin: an alternative for pulmonary embolism prophylaxis after arthroplasty?
        - Aspirin for elective hip and knee arthroplasty: a multimodal thromboprophylaxis protocol
        - Incidence of venous thromboembolism in elective foot and ankle surgery with and without aspirin prophylaxis.
        - Safety and efficacy of multimodal thromboprophylaxis following total knee arthroplasty: a comparative study of preferential aspirin vs. routine coumadin chemoprophylaxis.
        - Survey of prophylaxis against venous thromboembolism in adults undergoing hip surgery.
        - Aspirin prophylaxis and surveillance of pulmonary embolism and deep vein thrombosis in total hip arthroplasty.
        - Prophylaxis of deep-vein thrombosis after total hip replacement. Dextran and external pneumatic compression compared with 1.2 or 0.3 gram of aspirin daily.
        - High and low-dose aspirin prophylaxis against venous thromboembolic disease in total hip replacement.
        - Collaborative overview of randomised trials of antiplatelet therapy--III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists' Collaboration.
        - Aspirin prophylaxis for thromboembolic disease after total joint arthroplasty.
        -
Aspirin for thromboprophylaxis after primary lower limb arthroplasty: early thromboembolic events and 90 day mortality in 11,459 patients.
       
- Aspirin as Thromboprophylaxis in Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis
        -
Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty
        -
Aspirin Is as Effective as and Safer Than Warfarin for Patients at Higher Risk of Venous Thromboembolism Undergoing Total Joint Arthroplasty.
        -
Low-Dose Aspirin Is Effective Chemoprophylaxis Against Clinically Important Venous Thromboembolism Following TJA

  - Papers that show the ASA is not effective:
        - Little impact of antiplatelet agents on venous thromboembolism after hip fracture surgery
        - A prospective comparison of warfarin to aspirin for thromboprophylaxis in total hip and total knee arthroplasty



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Sunday, March 12, 2017 8:36 am