The Hip: Preservation, Replacement and Revision

Research Articles for Enhanced Microfracture:

- Autologous Hamstring Resurfacing: (hamstring harvest)
Tendon Metaplasia to Cartilage: References:
- Perisoteal Graft Studies for Chondral and Degenerative Arthritis of the Knee:
Knee Interpositional / Resurfacing Arthroplasty: Pertinent Human Studies

- Enhanced Microfracture Research Articles:  (AMIC related articles) (see AMIC dicussionmicrofracture discussion, and osteoarthritis)

                      - AMIC and Enhanced Microfracture Basic Science and Animal Model Papers:

                      - AMIC Clinical (Human) Papers:
                           -
A cell-free scaffold-based cartilage repair provides improved function hyaline-like repair at one year.  
                           -
AUTOLOGOUS MATRIX INDUCED CHONDROGENESIS (AMIC®) FOR FOCAL CHONDRAL DEFECTS OF THE KNEE – FIRST RESULTS
                           - Autologous Matrix Induced Chondrogenesis (AMIC®) for focal chondral defects of the knee – results at 2-4 years 
                           - MOSAICPLASTY AND AMIC TECHNIQUE AS SINGLE TIME SURGERY FOR CARTILAGE REPAIR
                           - Mid-term results of Autologous Matrix-Induced Chondrogenesis for treatment of focal cartilage defects in the knee
                           - Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
                           - BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device
                           - Bone and Cartilage Regeneration News Letter 2/2009  (contains ICRS Miami posters)
                           - AMIC technique for cartilage repair, a single-step surgical intervention as compared to other methods (2006)
                           - AMIC technique for cartilage repair, a single-step surgical intervention as compared to other methods (2007)
                           - Autologous Matrix-Induced Chondrogenesis (AMIC) - Treatment of Chondral and Osteochondral Defects in the Knee
                           - Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
                           - Cartilage Repair – Autologous Chondrocyte Transplantation and Autologous Matrix-induced Chondrogenesis
                           - Autologous matrix-induced chondrogenesis (AMIC) - a 2-year follow-up. Wimmer J, et al. Osteoarthr Cartilage. 2007;15:B89)
                           - Autologous Matrix Induced Chondrogenesis (AMIC®) for focal chondral defects of the knee -1-3 year results. Anders S, et al. Osteoarthr Cartilage. 2007;15:B84)
                           - Microfracture, Drilling Decalcified Cortical Bone Matrix and Adenovirus BMP Act Synergistically to Repair Cartilage Defects (paper 142)
                           - Autologous Matrix Induced Chondrogenesis (AMIC) –Treatment of Chondral and Osteochondral Defects in the Knee (paper 143)
                           - Arthroscopic fixation of chondrotissue: Preclinical and biomechanical data
                           - chondrotissue®: a new therapy concept for articular cartilage defects. First clinical experiences, multicenter clinical study
                           - In situ engineering of cartilage repair: a pre-clinical in vivo exploration of a novel system.
                           - Novel Nano-Composite Biomaterial For Osteochondral Tissue Engineering:Pilot Clinical Study
                           - Combination of microfracture and periostal-flap for the treatment of focal full thickness articular cartilage lesions of the shoulder: a prospective study.
                           - Case Report: Arthroscopic implantation of a resorbable cell free chondroinductive implant 
                           - Arthroscopic implantation of chondrotissue in microfracture - one year clinical follow up
                           - 13th International Conference on Biomedical Engineering
                           - European Instructional Lectures: Volume 9, 2009; 10th EFORT Congress, Vienna
                           - Arthroscopic implantation of chondrotissue in microfracture - one year clinical follow up.
                           - EFORT CONGRESS NICE, FRANCE 29 MAY – 1 JUNE 2008
                           - Arthroscopic Implantation of a Matrix to Cover Large Chondral Defect During Microfracture
                           - Rehabilitation guidelines for patients undergoing surgery for (ACI), (MACI) AND Autologous Matrix Induced Chondrogenesis (AMIC) of the knee 
                           - Our experience in the treatment of chondropathies with Bioseed®-C and chondrotissue®
  
                           - BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device
                           - Treatment of articular cartilage lesions of the knee joint using a modified AMIC technique
                           - swissbiomed: Treatment options for damaged cartilage - Chondrocyte Transplantation: ACT or AMIC?
                           - The Treatment of Retropatellar Chondral and Osteochondral Defects with Autologous Matrixinduced Chondrogenesis (AMIC)
                           - One-step bone marrow-derived cell transplantation in talar osteochondral lesions.
                           - Arthroscopic fixation of chondrotissue: Preclinical and biomechanical data
                           - Cell-free regeneration of articular cartilage defects: Pre-clinical and first clinical results
                           - 1 Step Cartilage Repair: Mesenchymal Stem Cell Implantation 
                           - Treatment of chondral defects with AMIC technique compared to AMIC enhanced by concentrated bone marrow
                           - METHOD AND COMPOSITION FOR INDUCING REGENERATION OF DAMAGED CARTILAGE USING MICROFRACTURE AND HYALURONIC ACID
                           -Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: in vitro characterisation of mesenchymal stem cells from iliac crest and subchondral bone.

                          - Corporate Technique Guides:
                                      - ASEED® for Scaffold Enhanced Microfracture Technique (SEMT)
                                      - Chondrotissue / surgical technique
                                      - Cartilix: 2009 Orthopaedic Research Society Meeting in Las Vegas, Nevada.
                                      - Cartilix - surgical
                                      - Vericart: autoregenerative cartilage matrix
                                      - BST-CarGel® for Cartilage Repair
                                      - AMIC dicussion
                                      - Tigenix - OCD Scaffold
                                      - Zimmer® DeNovo® NT Natural Tissue Graft

                           - Slide Shows:
                                      - AMIC slide show (http://www.sigascot.com/tutorials/congressonazionale_sigascot_2006/jacobi.ppt)
                                      - http://www.e-med.co.il/emed/new/Usersite/Presentations/Ortho1208b/Tim_Briggs.pdf
                                      - HST 535 Cartilage Repair - Massachusetts Institute of TechnologyMassachusetts Technology
                                      - Cartilage and Bone Biochemistry and Physiology
                                      - Osteoarthritis Side Show
                                      - Osteoarthritis Hip and Knee
                                      - Pathophysiology of Osteoarthritis
                                      - Hyalograft-C- a hyaluronan based tissue engineered cartilage graft- a review of preclinical and clinical findings
                                      - TiGenix
                                      - Cartilage Repair Methods
                                      - Cell Matrix Cartilage Implants Clinical Perspective
                                      - Scaffolds for Cartilage Tissue Engineering
                                      - The Arthritic Knee in the Ageing Athlete
                                      - Regenerative Medicine in Orthopaedics - a la carte repair?

                           - Review Articles:
                                      - AMIC technique for cartilage regeneration
                                      - Treatment of Isolated Cartilage Lesions of the Knee 
                                      - http://www.geistlich.com/?dom=3&rub=83
                                      - Cell Based Articular Cartilage Repair Strategies
                                      - Marrow stimulation techniques.
                                      - Autologous Chondrocyte transplantation / implantation vs existing treatments.
                                      - http://www.geistlich.com/upload/docs/pdf/20080813111244/Bone%20and%20Cartilage%20Regeneration%0News%2003-2006.pdf
                                      - 5000th Chondro-Gide® implanted – page 12
                                      - Treatment options for cartilage damage in the knee joint
                                      - Autologous Matrix Induced Chondrogenesis (AMIC) for focal chondral defects of the knee – first clinical and MRI-results
                                      - Bone and Cartilage Regeneration News Letter 2/2009  (contains ICRS Miami posters)
                                      - Bone & Cartilage Regeneration News 01/2009
                                      - Bone and Cartilage News Letter - 2008
                                      - Bone and Cartilage News Letter - 2/2008
                                      - Bone and Cartilage Regeneration - 2007 
                                      - Orthopaedic Tissue Engineering
                                      - Autologous cartilage transplantation
                                      - Evidence-Based Orthopaedics: The Best Answers to Clinical Questions 
                                      - Cartilage Repair Methods:
                                      - Scaffolds for Cartilage Tissue Engineering
                                      - Cell Matrix Cartilage Implants Clinical Perspective
                                      - Overview of Treatment Options for Articular Cartilage Repair:  Past, Present, and Future.
                                      - ARTICULAR CARTILAGE - Treatment Options
                                      - Designing a Porous Hydrogel for Articular Cartilage Engineering
                                      - Management of Articular Cartilage Injuries of the Knee
                                      - Hyalograft® C: Hyaluronan-Based Scaffolds in Tissue-Engineered Cartilage
                                      - Emerging Options for Treatment of Articular Cartilage Injury in the Athlete 
                                      - Articular cartilage defects: Emerging technologies are changing the treatment landscape
                                      - The Use of Scaffolds in the Management of Articular Cartilage Injury
                                      - JAAOS, June 2008: Use of Scaffolds in the Management of Articular Cartilage Injury
                                      - Autologous Matrix Induced Chondrogenesis  (see you tube video)
                                      - Caroline Hoemann on Articular Cartilage Resurfacing - Interview
                                      - Articular Cartilage Repair Using a Resorbable Matrix Scaffold.
                                      - Cartilage Repair Strategies by Riley J. Williams, L. Peterson p 72.  (amazon.com books)
                                      - Cartilage Repair Strategies by Riley J. Williams, L. Peterson p 72. (google books)
                                      - Biologic Joint Reconstruction: Alternatives to Joint Arthroplasty (By Brian Cole, Andreas Gomoll, MD) page 767 (google books)
                                      - Fundamentals of Tissue Engineering and Regenerative Medicine (page 234)
                                      - Articular cartilage tissue engineering
                                      - MIT: New tissue scaffold regrows cartilage and bone
                                      - Newly developed two-layer scaffold may regenerate cartilage and bone                     
                                      - Cartilage Repair Current and Emerging Options in Treatment
                                      - Articular Cartilage Tissue Engineering
                                      - Current Status of Articular Cartilage Repair
                                      - Overview of Existing Cartilage Repair Technology
                                      - Cartilage Repair – Replacing Joint Arthroplasty
                                      - European Instructional Lectures: Currently Status of Articular Cartilage Repair
                                      - Cartilage Replacement Procedure Uses Body's Own Stem Cells
                                      - Autologous cartilage transplantation
                                      - Patient Cells To Create New Knee Cartilage 
                                      - Regenerative Medicine
                                      - Bone & Cartilage Regeneration - AMIC Cartilage Regeneration Material
                                      - Microfracture meets MACI in hybrid cartilage repair technique
                                      - Cartilage repair: surgical techniques and tissue engineering using polysaccharide- and collagen-based biomaterials
                                      - Stem Cells in Regenerative Medicine 
                                      - Regeneration of ovine articular cartilage defects by cell-free polymer-based implants
                                      - Cartilage repair: surgical techniques and tissue engineering using polysaccharide- and collagen-based biomaterials
                                      - Marrow stimulation and chondrocyte transplantation using a collagen matrix for cartilage repair 
                                      - Articular cartilage regeneration using scaffold
                                      - RECONSTRUCTION OFARTICULAR CARTILAGE BY MEANS OF BIODEGRADABLESCAFFOLDS
                                      - In vivo matrix-guided human mesenchymal stem cells.  (PDF full text)       
                                      - Treatment options for cartilage damage in the knee joint    
                                      - Minimally invasive option for cartilage repair on the anvil  
                                      - Using collagen membrane improves ACT treatment for cartilage repair 
                                      - Histogenics NeoCart Cartilage Therapy Found Promising In OHSU Study Crawford To Report Data At ICRS Meeting
                                      - BIOMATERIALS FOR JOINT REGENERATION II REGENERATION
                                      - Augmented Microfracture Technique 
                                      - Bone & Cartilage Regeneration - AMIC Cartilage Regeneration Material
                                      - Microfracture meets MACI in hybrid cartilage repair technique
                                      - Operative Treatment of Articular Cartilage Defects: Augmented microfracture techniques
                                      - Autologous Matrix Induced Chondrogenesis (AMIC) –Treatment of Chondral and Osteochondral Defects in the Knee
                                      - Marrow Stimulation and Microfracture for the Repair of Articular Cartilage Lesions 
                                      - Perspectives on articular cartilage biology and osteoarthritis
                                      - Science | 13.05.2007. Researchers Develop New Cartilage Replacement Method
                                      - Treatment of articular cartilage in microfractures
                                      - ARTICULAR CARTILAGE RESTORATION: A REVIEW OF CURRENTLY AVAILABLE METHODS FOR REPAIR OF ARTICULAR CARTILAGE DEFECTS
                                      - In vivo matrix guided human mesenchymal stem cells.
                                      - Healing of articular cartilage defects treated with a novel drug-releasing rod-type implant after microfracture surgery.
                                      - Autologous Matrix-Induced Chondrogenesis (AMIC) 
                                      - Strategies for Articular Cartilage Lesion Repair and Functional Restoration
                                      - Rehabilitation Following Microfracture for Chondral Injury in the Knee.
                                      - The Future of Cartilage Repair
                                      - The Future of Cartilage Regeneration by Stem Cells.
                                      - MICROFRACTURE TECHNIQUES IN THE TREATMENT OF OSTEOCHONDRAL INJURIES


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Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Thursday, January 10, 2013 1:45 pm